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1.
Arq. Inst. Biol. (Online) ; 89: e00022022, 2022. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-1416790

ABSTRACT

The state of Piauí is in a Cerrado/Caatinga transition area, which is known the richness of its fauna and flora. Therefore, this work aims to know the diversity of fruit fly species in cashew orchards and native forest fragments in the south-central region of Piauí. Fruit flies were collected in McPhail traps and by sampling fruits. The material collected from the traps and the fruits in the two areas were taken to the Laboratory of Phytotechnics from Campus Prof. Cinobelina Elvas at the Universidade Federal do Piauí (UFPI/CPCE), municipality of Bom Jesus, Piauí, Brazil. In McPhail traps, six species of the genus Anastrepha: A. alveata, A. dissimilis, A. fraterculus, A. manihoti, A. obliqua, and A. zenildae were captured, of which A. fraterculus, A. obliqua, and A. zenildae were present in both areas. Anastrepha alveata, A. dissimilis and A. manihoti occurred only in the cashew orchard. In fruit sampling, A. fraterculus, A. obliqua, and A. zenildae infested wild-guava fruits, Myrcia tomentosa (Myrtaceae), in native forest. Anastrepha fraterculus, A. obliqua and A. zenildae were obtained directly from M. tomentosa fruits and from traps. The availability of host fruits is the factor that most influences the population fluctuation of fruit flies, mainly in the native forest area. Anastrepha manihoti is reported for the first time in the state of Piauí. This is the first record of A. fraterculus, A. obliqua and A. zenildae, infesting wildguava fruits, M. tomentosa.


Subject(s)
Tephritidae/classification , Psidium/parasitology , Biodiversity
3.
Autops. Case Rep ; 11: e2021294, 2021. graf
Article in English | LILACS | ID: biblio-1285393

ABSTRACT

Necrotizing sarcoid granulomatosis (NSG) is a rare and under-recognized cause of granulomatous disease, described as a variant of typical nodular sarcoidosis. It can be asymptomatic when the patient has a single pulmonary nodule or may be accompanied by cough, fever, and dyspnea, or even symptoms due to the involvement of other organs such as the eyes, liver, and central nervous system. The histopathological analysis is essential for the differential diagnosis of other infectious and non-infectious causes of granuloma and to determine the appropriate treatment. NSG is characterized by the presence of a granuloma with extensive coagulative necrosis associated with the occurrence of vasculitis. We present the case of a patient diagnosed with NSG who had an unusual outcome with recurrent pulmonary thromboembolisms followed by hemodynamic instability and death.


Subject(s)
Humans , Female , Adult , Sarcoidosis, Pulmonary/pathology , Granuloma , Granulomatosis with Polyangiitis/pathology , Diagnosis, Differential
4.
Rev. bras. oftalmol ; 78(1): 22-26, jan.-fev. 2019. tab, graf
Article in Portuguese | LILACS | ID: biblio-990789

ABSTRACT

Resumo Objetivo: Na presença de uma córnea irregular, como no queratocone, o epitélio tem uma distribuição diferente do normal, "mascarando" a irregularidade do estroma. A avaliação topográfica sem considerar o efeito do epitélio pode induzir uma avaliação menos correta, afetando a precisão de um eventual tratamento guiado por topografia. O objetivo deste trabalho é avaliar o efeito de "máscara" do epitélio no queratocone, comparando a tomografia corneana com e sem epitélio, no decurso da realização de Crosslinking (CXL). Métodos: Cinco olhos de 5 doentes com queratocone em progressão submetidos a CXL segundo o protocolo original de Dresden. Foi realizada tomografia corneana antes e durante o procedimento (imediatamente após a remoção do epitélio), e avaliados os valores da queratometria - K1, K2, K médio (Km), ponto de máxima curvatura (Kmax), valores paquimétricos e astigmatismo corneano. Resultados: Os valores médios de curvatura corneanas antes e após a remoção do epitélio foram de: K1: 43,50 ± 2,54D e 44,32±2,64D (p=0,080); K2: 46,64±2,35D e 49,38±2,86D (p=0,043); Km: 45,48±2,42D e 46,72±2,60D (p=0,042). Observou-se igualmente um aumento estatisticamente significativo do valor de queratometria máxima após a remoção do epitélio (p=0,043). Na paquimetria central observou-se uma redução média de 26,8µm de 524,8±33,0µm para 498,2±37,7µm (p= 0,042). Conclusão: Observou-se um aumento estatisticamente significativo nos valores do Kmax, K2, e Kmédio após remoção do epitélio. Este estudo demonstra o efeito de "máscara" que o epitélio exerce no queratocone.


Abstract Objective: In the presence of an irregular cornea, like in keratoconus, the corneal epithelium has a different profile "masking" the irregular corneal stroma surface. Topographical analysis without considering the epithelium effect can result in an incorrect assessment, affecting the accuracy of any topography guided treatment. The aim of this study was to evaluate the "masking" effect of the corneal epithelium on corneal curvature in patients with keratoconus, comparing topographical findings before and after removal of the epithelium during Crosslinking (CXL). Methods: Five eyes of 5 patients with progressive keratoconus submitted to CXL according to the original Dresden protocol. Corneal topography was performed before and during the procedure (immediately after epithelium removal) and values of keratometry: K1, K2, mean K (Km), maximum corneal apical curvature (Kmax), corneal thickness and corneal astigmatism were evaluated. Results: The average values of corneal curvature before and after epithelial remove were: K1: 43.50±2.54D and 44.32±2,64D (p=0.080); K2 46.64±2,35D and 49.38±2,86D (p=0.043); Km 45.48±2.42D and 46.72±2.60D (p=0.042). It was also observed a significant increase in the maximum values of corneal apical curvature after removal of the epithelium (p=0.043). In central corneal thickness there was seen a reduction of 26.8µm from 524.8±33.0µm to 498.2±37.7µm (p = 0.042). Conclusion: There was seen a significant increase in the values of Kmax, K2 and mean K. This study demonstrates the masking effect of corneal epithelium on corneal curvature in keratoconus.


Subject(s)
Humans , Tomography, X-Ray Computed , Corneal Topography , Cross-Linking Reagents , Keratoconus/diagnosis , Retrospective Studies , Cornea/surgery , Epithelium/surgery
5.
Biota Neotrop. (Online, Ed. ingl.) ; 19(4): e20190776, 2019. tab, graf
Article in English | LILACS-Express | LILACS | ID: biblio-1038866

ABSTRACT

Abstract: Fruit flies are among the main groups of phytophagous insects. Their larvae, when feeding on the pulp or seeds of the host fruits, can cause rot and favor the entrance of pathogens. Thus, the objectives of this study was: (1) To know the trophic associations between species of parasitoids and fruit flies in the Parque Nacional da Serra da Bodoquena (PNSB)-MS, Brazil. (2) To inventory the parasitoid species associated with fruit flies in fruit trees in the Parque Nacional da Serra da Bodoquena. Monthly expeditions were carried out (From Jan 2017 to Feb 2018) in order to collect the fruits and obtain the fruit flies (Tephritidae) and their respective parasitoids. The collected fruits were transported to the laboratory of frugivorous insects (LIF) of the Universidade Federal da Grande Dourados (UFGD)-MS. The fruit fly larvae were daily collected and placed in transparent acrylic cups containing sterilized sand, where they remained till the emergence of adults and their parasitoids. Twenty-Three adult Tephritid parasitoids were recovered, represented by two species of Braconidae: Doryctobracon areolatus (18) and Utetes anastrephae (5), both infesting Anastrepha species: Anastrepha fraterculus, A. sororcula and A. striata in Myrtaceae: Psidium guajava and Eugenia myrcianthes. Doryctobracon areolatus and Utetes anastrephae are reported for the first time parasiting Anastrepha species in Eugenia myrcianthes.


Resumo: As moscas-das-frutas estão entre os principais grupos de insetos fitófagos. Suas larvas, ao se alimentarem da polpa ou das sementes dos frutos hospedeiros, podem causar podridão e favorecer a entrada de patógenos. Sendo assim, os objetivos desse estudo foram: (1) Conhecer as associações tróficas entre as espécies de parasitoides e moscas das frutas no Parque Nacional da Serra da Bodoquena (PNSB). (2) Inventariar as espécies de parasitoides no PNSB. Foram realizadas expedições mensais de janeiro de 2017 a fevereiro de 2018 para as coletas de frutos e obtenção de moscas das frutas (Tephritidae) e seus respectivos parasitoides. Os frutos coletados foram transportados ao Laboratório de Insetos Frugívoros (LIF) da Universidade Federal da Grande Dourados-MS. As larvas das moscas das frutas foram diariamente recolhidas e inseridas em copos de acrílico transparentes contendo areia esterilizada onde permaneceram até a emergência dos adultos de tefritídeos e/ou seus parasitoides. Foram recuperados 23 adultos de parasitoides das larvas dos tefritídeos, representados por duas espécies de Braconidae: Doryctobracon areolatus (18) e Utetes anastrephae (5), ambos parasitando espécies de Anastrepha: Anastrepha fraterculus, A. sororcula e A. striata em Myrtaceae: Psidium guajava e Eugenia myrcianthes. Doryctobracon areolatus e Utetes anastrephae são relatados pela primeira vez parasitando espécies de Anastrepha em frutos de Eugenia myrcianthes.

6.
Arq. Inst. Biol ; 85: e0882016, 2018.
Article in English | LILACS, VETINDEX | ID: biblio-987430

ABSTRACT

For the first time, the presence of Neosilba zadolicha McAlpine & Steyskal is being recorded in mandacaru fruits [Cereus jamacaru DC.], in the municipality of Alvorada do Gurgueia, in the south-central region of the State of Piauí, Brazil (8º22'35.63" S, 43º51'25,96" W). Eleven specimens were obtained from mandacaru fruits in an area of native forest between February and May of 2016. This is the first record of N. zadolicha in a Cactaceae species.(AU)


Registra-se a ocorrência de Neosilba zadolicha McAlpine & Steyskal pela primeira vez em frutos de mandacaru (Cereus jamacaru DC.), no município de Alvorada do Gurgueia, centro-sul do estado do Piauí (8º22'35.63" S, 43º51'25,96" W). Foram obtidos 11 exemplares de frutos de mandacaru, em área de mata nativa, de fevereiro de 2016 a maio de 2016. Este é o primeiro registro de N. zadolicha em uma espécie de Cactaceae.(AU)


Subject(s)
Agricultural Pests , Cactaceae , Diptera
7.
Acta cir. bras ; 32(4): 297-306, Apr. 2017. tab, graf
Article in English | LILACS | ID: biblio-837697

ABSTRACT

Abstract Purpose: To evaluated the effects of L-lysine on the intestinal and urothelial epithelia in cystoplasty in rats. Methods: Twenty-eight 9-week-old rats were assigned to 4 groups: Group A (n=8) cystoplasty followed by administration of L-lysine (150 mg/kg body weight by gavage) for 30 weeks; Group B (n=8) cystoplasty + water for 30 weeks; Group C (n=6) L-lysine for 30 weeks; Group D (n=6) water for 30 weeks. Results: On histopathology with hematoxylin and eosin, mild to moderate hyperplasia transitional was observed in at the site of anastomosis in all animals submitted to cystoplasty (Groups A and B), but "transitional metaplasia" of the intestinal glandular epithelium was more accentuated in Group A (p=0.045). No inflammatory cells, dysplasia or abnormalities were observed. Staining with Alcian blue revealed a substantial reduction of goblet cells and mucins in the colon segment (Groups A and B). Conclusion: The administration of L-lysine to rats accelerated the development of transitional metaplasia in the epithelium of the colon segment in cystoplasty.


Subject(s)
Animals , Female , Rats , Carcinogenesis/chemically induced , Intestinal Mucosa/surgery , Intestinal Mucosa/pathology , Lysine/adverse effects , Urinary Diversion , Urinary Bladder/surgery , Disease Models, Animal , Carcinogenesis/pathology , Lysine/administration & dosage , Metaplasia/chemically induced , Metaplasia/pathology
8.
Acta cir. bras ; 31(12): 793-800, Dec. 2016. tab, graf
Article in English | LILACS | ID: biblio-837657

ABSTRACT

ABSTRACT PURPOSE: To evaluate the effects of L-lysine on the intestinal and urothelial epithelium of rats subjected to ureterosigmoidostomy (new model for surgical carcinogenesis). METHODS: Forty-two rats, 9 weeks of age, were divided into 6 groups. Animals in groups A, B, C were subjected to ureterosigmoidostomy (US) and treated with L-lysine, celecoxib and H2O, respectively. Groups D, E and F (non-operated controls) received L-lysine, celecoxib and H2O, respectively. The L-lysine dose was 150 mg/kg and that of celecoxib was 20 mg/kg. The colon was analyzed for the presence of aberrant crypt foci (ACF) under a stereomicroscope.The tissue was stained with hematoxylin and eosin and PAS alcian blue. RESULTS: There were rare ACF, and there was no statistically significant difference between the groups. Histopathologic study of the ureteral epithelium identified moderate to severe urothelial hyperplasia in rats with ureterosigmoidostomy. Transitional hyperplasia in the ureters of animals receiving L-lysine (A) showed an apparent difference compared to the control (C) (P=0.2424). There was no dysplasia or atypia CONCLUSION: L-lysine does not promote carcinogenesis of the intestinal and urethelial epithelium of rats subjected to ureterosigmoidostomy at the doses and times studied.


Subject(s)
Animals , Female , Rats , Colon, Sigmoid/surgery , Surgical Stomas , Aberrant Crypt Foci/pathology , Carcinogenesis , Intestinal Neoplasms/etiology , Lysine/pharmacology , Urinary Bladder Neoplasms/etiology , Ureterostomy/methods , Rats, Wistar , Disease Models, Animal , Surgical Stomas/adverse effects , Intestinal Mucosa/pathology
9.
Rev. Col. Bras. Cir ; 43(2): 80-86, Mar.-Apr. 2016. tab, graf
Article in English | LILACS | ID: lil-782916

ABSTRACT

ABSTRACT Objective: to evaluate the effect of L-lysine in the bladder and intestinal epithelia in rats submitted to vesicosigmoidostomy. Methods: we divided forty Wistar rats into four groups: group I - control group (Sham); group II - submitted to vesicosigmoidostomy and treated with L-lysine 150mg/kg; group III - submitted only to vesicosigmoidostomy; and group IV - received L-lysine 150mg/kg. After eight weeks the animals were sacrificed. Results: in the bladders of all operated animals we observed simple, papillary and nodular hyperplasia of transitional cells, transitional cell papillomas and squamous metaplasia. As for the occurrence of aberrant crypt foci in the colons of operated animals, we did not observe statistically significant differences in any of the distal, proximal and medium fragments, or in all fragments together (p=1.0000). Conclusion: Although statistically there was no promotion of carcinogenesis in the epithelia of rats treated with L-lysine in the observed time, it was clear the histogenesis of bladder carcinogenesis in its initial phase in all operated rats, this being probably associated with chronic infection and tiny bladder stones.


RESUMO Objetivo: o objetivo deste trabalho é avaliar o efeito da L-lisina nos epitélios vesical e intestinal de ratas submetidas à vesicossigmoidostomia. Métodos: quarenta ratas Wistar, foram divididas em quatro grupos: grupo I- grupo controle (Sham); grupo II- submetido à vesicossigmoidostomia e tratado com L-lisina 150mg/kg; grupo III- submetido apenas à vesicossigmoidostomia; e grupo IV- recebeu L-lisina 150mg/kg. Após oito semanas os animais foram sacrificados. Resultados: na bexiga de todos os animais operados observou-se hiperplasia simples, papilar e nodular de células transicionais, papiloma de células transicionais e metaplasia escamosa. Quanto à ocorrência de focos de criptas aberrantes nos colos dos animais operados, não foi evidenciado diferença estatística significante em nenhum dos fragmentos distal, proximal e médio, e todos juntos (P=1,0000). Conclusão: apesar de, estatisticamente, não ter havido promoção de carcinogênese nos epitélios dos ratos tratados com L-lisina, no tempo observado, é nítida a histogênese da carcinogênese de bexiga em sua fase inicial, no epitélio vesical, em todos os ratos operados, estando esta provavelmente associada à infecção crônica e aos diminutos cálculos vesicais.


Subject(s)
Animals , Rats , Postoperative Complications/chemically induced , Colon, Sigmoid/surgery , Urinary Bladder/drug effects , Urinary Bladder/pathology , Ureterostomy , Carcinogenesis/chemically induced , Intestinal Mucosa/drug effects , Intestinal Mucosa/pathology , Lysine/pharmacology , Rats, Wistar
10.
Fractal rev. psicol ; 26(2): 429-444, May-Aug/2014. tab
Article in Portuguese | LILACS | ID: lil-721443

ABSTRACT

Esse estudo analisou como jovens de escolas públicas identificam e avaliam vivências de violência no ambiente familiar e comunitário, partindo de um recorte de uma pesquisa sobre risco e proteção na população juvenil. Para tanto, foram selecionados 529 estudantes, de 14 a 24 anos e ambos os sexos, que afirmaram ter sofrido algum tipo de violência naqueles ambientes. Aplicou-se um instrumento com 77 questões sobre situações cotidianas e fez-se análise dos itens relativos à vivência de situações de violência. Os resultados demonstraram a ocorrência mais frequente de violência física na família. Já, na comunidade, ameaça ou humilhação. A percepção negativa dos jovens sobre o ambiente de ocorrência da violência, destacou-se o familiar. Os dados sobre autoestima e auto eficácia revelaram aspectos protetivos. As análises conduzem à conclusão de que a percepção da violência como fator de risco precisa ser compreendida no contexto de participação do jovem e na sua história.


This research analyzes how public school students identify and evaluate experiences of violence in a domestic environment and within their communities. This is a snip of a larger research on risk and protective factors in youth populations. Of the 1.140 participants, 529 were students from both genders with ages between 14 and 24. The results revealed that punching and spanking occurred more frequently in the familiar environment, whereas threatening and humiliation within the community. It was applied a survey with 77 questions concerning those experiences in everyday situations. As for the negative perceptions on the types of abuse regarding the environment where they occurred, the study indicates that undergoing domestic violence had a stronger impact. The results on self-esteem and self-efficacy revealed protective aspects of personal nature. The perception of violence as a risk factor should be understood based on the context of the subject's role and their life story.


Subject(s)
Humans , Male , Female , Young Adult , Adolescent , Domestic Violence , Protective Factors , Risk Factors , Students , Violence
11.
Sci. med ; 23(1)jan.-mar. 2013.
Article in English | LILACS-Express | LILACS | ID: lil-678976

ABSTRACT

Aims: To determine the in vitro antiviral activity of dermaseptin 01, an antimicrobial peptide discovered in the skin secretion of Phyllomedusa hypochondrialis frogs, against Herpes simplex virus type 1, Vaccinia virus and Dengue virus type 2.Methods: The peptide dermaseptin 01 was used for the cytotoxic assays using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide colorimetric assay (MTT) in VERO, LLCMK2 and C6/36 cells. The antiviral activity was also evaluated using MTT for Herpes simplex virus type 1 and Vaccinia virus in VERO cells and for Dengue virus type 2 in LLCMK2 cells. The antiviral activity of dermaseptin 01was also evaluated in C6/36 cells infected with Dengue virus type 2 by cytopathic effect reduction.Results: The 50% cytotoxicity concentration of dermaseptin 01 was 105 ?g/mL in insect cells (C6/36) and >1000 ?g/mLin mammalian cells (VERO and LLCMK2). Dermaseptin 01 displayed antiviral effect only against Dengue virus type 2 with a 50% effective concentration of 15 ?g/mL in C6/36 cells and 60 ?g/mL in LLCMK2 cells.Conclusions: These data suggested that dermaseptin 01 have an in vitro antiviral action against Dengue virus type 2 but not against Herpes simplex virus type 1 or Vaccinia virus.


Objetivos: Determinar a atividade antiviral in vitro da dermaseptina 01, um peptídeo antimicrobiano isolado da secreção de pele de pererecas Phyllomedusa hypochondrialis, contra vírus Herpes simplex tipo 1, Vaccinia virus e Dengue virus tipo 2.Métodos: O peptídeo dermaseptina 01 foi usado em ensaios de citotoxicidade com ensaio colorimétrico utilizando brometo tiazoil azul tetrazólio (MTT) em células VERO, LLCMK2 e C6/36. A atividade antiviral foi determinada também por MTT para Herpes simplex tipo 1 e Vaccinia virus nas células VERO e para Dengue virus tipo 2 nas células LLCMK2. A atividade antiviral da dermaseptina 01 também foi testada nas células C6/36 infectadas com Dengue virus tipo 2 através da quantificação da redução do efeito citopático.Resultados: A concentração citotóxica da dermaseptina 01 para 50% das células foi 105 ?g/mL nas células de inseto (C6/36) e >1000 ?g/mL nas células de mamíferos (VERO e LLCMK2). A dermaseptina 01 apresentou efeito antiviral somente contra Dengue virus tipo 2 com uma concentração efetiva para 50% das células de 15 ?g/mL nas células C6/36 e 60 ?g/mL nas células LLCMK2.Conclusões: Os dados sugerem que a dermaseptina 01 possui ação antiviral in vitro contra Dengue virus, mas não contra Herpes simplex ou Vaccinia virus.

12.
Rev. Col. Bras. Cir ; 39(6): 529-533, nov.-dez. 2012. ilus, tab
Article in Portuguese | LILACS | ID: lil-662783

ABSTRACT

OBJETIVO: Avaliar o efeito protetor do per-condicionamento isquêmico remoto nas lesões de isquemia e reperfusão renal induzida. MÉTODOS: Quinze ratos (Rattus Novergicus) foram randomizados em três grupos (n=5): Grupo Normalidade (GN), Grupo Controle - Isquemia e Reperfusão (GIR) e Grupo Per-condicionamento isquêmico remoto (GPER). Com exceção do grupo GN, todos os demais foram submetidos à isquemia renal de 30 minutos. No grupo GPER, foi realizado o per-condicionamento isquêmico remoto, constituído de três ciclos de isquemia e reperfusão de cinco minutos cada aplicado, durante o período de isquemia, no membro posterior esquerdo dos ratos, por meio de torniquete. Para quantificar as lesões, foram dosados os níveis séricos de ureia e creatinina, bem como, analisada a histopatologia renal. RESULTADOS: O grupo GPER apresentou-se com melhores níveis de ureia (83,74 ± 14,58%) e creatinina (0,72 ± 26,14%) quando comparado ao grupo GIR, se aproximando do grupo GN. Na histopatologia, os menores níveis de degeneração hidrópica e congestão medular foram encontrados no grupo GPER. CONCLUSÃO: O per-condicionamento isquêmico remoto apresentou importante efeito protetor na lesão de isquemia e reperfusão renal.


OBJECTIVE: To evaluate the protective effect of remote ischemic per-conditioning in ischemia and reperfusion-induced renal injuiry. METHODS: Fifteen rats (Rattus norvegicus) were randomized into three groups (n = 5): Group Normality (GN), Control Ischemia and Reperfusion (GIR) and Group remote ischemic per-conditioning (GPER). With the exception of the GN group, all others underwent renal ischemia for 30 minutes. In group GPER we performed the ischemic remote per-conditioning, consisting of three cycles of ischemia and reperfusion applied every five minutes during the ischemic period, to the left hindlimb of the rats by means of a tourniquet. To quantify the lesions we measured serum levels of creatinine and urea, as well as analyzed renal histopathology. RESULTS: The GPER group presented with better levels of urea (83.74 ± 14.58%) and creatinine (0.72 ± 26.14%) when compared to GIR group, approaching the GN group. Histopathologically, the lower levels of medullary congestion and hydropic degeneration were found in group GPER. CONCLUSION: The remote ischemic per-conditioning had a significant protective effect on renal ischemia and reperfusion.


Subject(s)
Animals , Male , Rats , Ischemic Preconditioning , Kidney/blood supply , Reperfusion Injury/prevention & control , Rats, Wistar
13.
Rev. educ. fis ; 23(3): 469-481, jul.-set. 2012. ilus, tab
Article in Portuguese | LILACS | ID: lil-701470

ABSTRACT

O óxido nítrico (NO) é um potente vasodilatador com papel importante no controle do tônus vascular. Estudos têm demonstrado a função do NO na preservação da capacidade funcional do endotélio, prevenindo aterosclerose, lesão vascular, hipertensão, entre outras. Por outro lado, fatores genotípicos e/ou fenotípicos podem diminuir sua biodisponibilidade, resultando em disfunção endotelial grave, e aumentar a resistência vascular periférica. Recentes estudos têm demonstrado que o exercício aumenta a biodisponibilidade do NO de forma aguda e crônica. Porém, a produção do conhecimento relacionado ao NO, mediado pelo exercício, ainda apresenta lacunas. Neste sentido, o objetivo desta revisão é tentar elucidar os mecanismos celulares envolvidos na síntese e regulação do NO e demonstrar o avanço do conhecimento cientifico relacionado à biodisponibilidade de NO mediado pelo exercício. Para tanto, para esta revisão foram utilizados livros e periódicos das bases de dados PubMed, HIGWIRE, SciELO e LILACS, utilizando as palavras-chave "nitric oxide" e "exercise" para a busca de publicações. As principais considerações do estudo foram que o exercício físico pode aumentar a biodisponibilidade de NO de forma aguda, e as adaptações crônicas do exercício em relação aos parâmetros cardiovasculares são dependentes do aumento da biodisponibilidade de NO induzida pelo exercício.


Nitric oxide (NO) is a potent vasodilator, and hence plays a major role in controlling the vascular tone. Studies have demonstrated the role of NO in preserving the functional capacity of the endothelium, preventing atherosclerosis, vascular injury, hypertension among others. Moreover, the genotype and/or phenotype may reduce the bioavailability of NO, resulting in severe endothelial dysfunction and increased peripheral vascular resistance. Recent research has shown that the exercise increases the bioavailability of NO in the acute and chronic forms. However, the knowledge production related to the NO-mediated exercise still has gaps. Thus, the purpose of this short review is to attempt to elucidate the cellular mechanisms involved with the NO synthesis and regulation, and to demonstrate the progress in the scientific knowledge related to the bioavailability of NO mediated by exercise. In order to carry out this review, books and periodicals were used from PubMed, HIGWIRE, SciELO and LILACS databases, using "nitric oxide" and "exercise" as keywords in the search engine. The main considerations in the study were that the exercise increases the acute bioavailability of NO, and the chronic adaptations of exercise in relation to the cardiovascular parameters are dependent on the increased bioavailability of NO induced by the exercise.

14.
Rev. bras. med. esporte ; 16(6): 418-421, nov.-dez. 2010. graf, tab
Article in Portuguese | LILACS | ID: lil-606723

ABSTRACT

INTRODUÇÃO: A crescente procura da natação como um tratamento não-farmacológico da hipertensão arterial tem aumentado. Objetivo: Analisar as respostas da pressão arterial (PA) após o exercício de natação e durante a rotina diária de trabalho de indivíduos pré-hipertensos. MÉTODOS: Oito indivíduos pré-hipertensos (128,2 ± 7,8 / 77,8 ± 6,0mmHg; 41,8 ± 3,2 anos; 84,7 ± 17,9kg; 180,4 ± 4,8cm; 27,3 ± 5,8kg.m2(-1)) foram submetidos a duas sessões, sendo uma de natação (SN) e a outra de controle (SC). A PA foi medida no repouso pré-exercício e durante 12 horas de recuperação pós-exercício. Na SN, os pacientes nadaram por 45min em uma intensidade moderada a alta (PSE 14,5 ± 1,6), e, durante a SC, os sujeitos permaneceram em repouso na posição sentada pelo mesmo período de tempo. RESULTADOS: ANOVA para medidas repetidas evidenciou diminuição significativa (p < 0,05) na PAS por duas horas após a SN em relação ao repouso, e uma diferença significativa entre os deltas do PAS (Δ - PAS variação na recuperação pós-exercício em relação ao repouso pré-exercício) foi observada entre as sessões na primeira e segunda horas após a recuperação, respectivamente (ΔSS = -10,4 e -9,3 vs. ΔCS = 0,8 e 4,4mmHg, p < 0,05). Nγo houve diferenças significativas da PAD, intra e entre as sessões. CONCLUSÃO: O exercício de natação em intensidade moderada a alta foi eficaz para promover redução da PA pós-exercício em indivíduos hipertensos durante a sua rotina de trabalho.


INTRODUCTION: The increasing demand for swimming as a non-pharmacological treatment of hypertension has increased. PURPOSE: To analyze the blood pressure (BP) responses after swimming and during the daily work routine of pre-hypertensive individuals. METHODS: Eight male borderline hypertensive individuals (128.2 ± 7.8 / 77.8 ± 6.0 mmHg; 41.8 ± 3.2 years; 84.7 ± 17.9 kg; 180.4 ± 4.8 cm; 27.3 ± 5.8 kg.m2 (-1)) were submitted to a swimming exercise (SS) and control (CS) sessions. BP was measured at pre-exercise rest and during 12 hours of the post-exercise recovery. In SS, patients swan for 45 minutes in a moderate-high intensity (PSE 14.5 ± 1.6), and during CS the subjects remained at seated rest for 45 min. RESULTS: ANOVA for repeated measures evidenced significant decrease (P < 0.05) in SBP in the for 2 hours after SS in comparison to rest, and a significant difference between the SBP deltas (Δ - SBP variation in the post-exercise recovery compared to pre-exercise rest) was observed when comparing sessions at 1 and 2 hours after recovery, respectively (ΔSS = -10.4 and -9.3 vs. ΔCS = 0.8 and 4.4 mmHg, p <0.05). There were not significant differences in DBP within and between sessions. CONCLUSION: Swimming exercise at moderate-high intensity was effective in promoting post-exercise BP reduction for borderline hypertensive individuals during their daily work routine.


Subject(s)
Humans , Male , Adult , Arterial Pressure , Exercise , Heart Rate , Hypertension , Swimming
16.
Rev. bras. ciênc. mov ; 18(2): 76-83, abr.-jun. 2010. tab
Article in Portuguese | LILACS | ID: lil-731484

ABSTRACT

A força, a velocidade, a flexibilidade, a resistência, a coordenação e o equilíbrio, estão dentro das capacidades treináveis para o desenvolvimento do jiu-jítsu. O objetivo deste estudo consistiu em comparar a aptidão física e indicadores de crescimento de adolescentes com idade média de 16,04±0,62 anos que estão regulamente matriculados no ensino médio, praticantes ou não de jiu-jítsu. A amostra foi constituída por 25 alunos do ensino médio divididos em três grupos sendo, praticantes de jiu-jítsu iniciantes (GI=9), avançados (GA=7), e controle (GC=9) que não praticavam jiu-jítsu. Os adolescentes foram submetidos à avaliação de peso, altura, %G, pressão arterial de repouso, e uma bateria de testes de aptidão física sugerida por Gaya & Silva (2007). Para a análise estatística foi utilizada ANOVA one-way para as comparações entre os grupos, e a significância estatística foi de p<0,05. Com relação à pressão arterial sistólica de repouso foram encontradas diferenças significativas de GA quando comparada com GC (104,3±16,2; 121,2±11,7 mmHg). A força explosiva de membros superiores do GA foi estatisticamente diferente do GC (5,5±0,6; 4,2±0,8 m). Com relação ao teste de força de resistência abdominal foram encontradas diferenças significativas de GA e GI quando comparado com GC (55,4±8,6; 55,2±7,2; 41,7±6,6 rep ◌ּ min-1). Concluiu-se que a participação dos adolescentes na modalidade jiu-jítsu contribuiu no aumento das capacidades relacionadas à força e os valores são aumentados com o tempo de prática, além de, os praticantes também serem beneficiados com o efeito protetor do exercício físico frente à pressão arterial.


Strength, speed, flexibility, endurance, coordination and balance are trainable skills for the development of jiu-jitsu. The aim of this study was to compare physical fitness and growth indicators of adolescents with a mean age of 16.04±0.62 years who are regularly enrolled in high school and practice jiu-jitsu and students’ who do not practice. The sample consisted of 25 high school students’ divided into three groups being, beginners jiu-jitsu practitioners (GI = 9), advanced practitioners (GA = 7) and control (GC = 9) that do not practice jiu-jitsu. The adolescents had weight, height, % G, resting blood pressure measured and a battery of physical fitness tests suggested by Gaya & Silva (2007). One-way ANOVA for comparisons between groups were used and level of significance adopted was p <0.05. The resting systolic blood pressure had significant differences comparing GA to GC (104.3±16.2, 121.2±11.7 mmHg). In relation to endurance test of abdominal strength significant differences were founded in GA and GI compared to GC (55.4±8.6, 55.2±7.2, 41.7±6.6 rep ◌ּ min-1). It was concluded that the adolescents who enrolled in jiu-jitsu had higher values of strength and these data increased with the years of practice, further than that the practitioners also had benefits related to resting blood pressure having a protective effect of the exercise.


Subject(s)
Humans , Male , Adolescent , Education, Primary and Secondary , Growth and Development , Martial Arts , Physical Fitness , Students , Adolescent , Arterial Pressure , Brazil , Muscle Strength , Pliability , Mentoring
17.
Brasília méd ; 47(4)2010. tab
Article in Portuguese | LILACS-Express | LILACS | ID: lil-587865

ABSTRACT

Objetivo. Verificar e comparar com valores normativos, variáveis antropométricas, hemodinâmicas e neuromusculares de servidores administrativos do Tribunal Superior Eleitoral do Distrito Federal.Método. Foram submetidos 31 indivíduos (11 homens e 20 mulheres) com 32,9 ± 11,8 anos à mensuração da massa corporal (kg) e estatura (cm) para posterior cálculo do índice de massa corpórea (kg/m2), da pressão arterial, da força de preensão manual e ao teste da flexibilidade.Resultados. Os servidores em estudo tiveram índices de massa corpórea estratificados como eutróficos (24,1 ± 4,4 kg/m2). Quando, porém, se analisaram os grupos masculino e feminino separadamente, os homens tiveram valores estratificados como sobrepesados (25,9 ± 3,5 kg/m2). Quando avaliado o percentual de gordura, ambos os grupos tiveram valores acima da média (19,3 ± 7,2 e 27,3 ± 4,9% para homens e mulheres respectivamente). Os valores de pressão arterial sistólica (112,9 ± 13 mmHg), diastólica (72,7 ± 10,2 mmHg) e média (86,1 ± 10,7 mmHg) foram normais. Contudo, 36,4% dos homens ostentaram pressão arterialelevada. A força de preensão manual analisada em toda a amostra (25 ± 7,7 kgf), em homens (31,1 ± 9 kgf) e mulheres (20,9 ± 3 kgf), foi estratificada como abaixo da média. No teste de flexibilidade sentar e alcançar, a amostra total, assim como os homens e as mulheres, apresentaram resultados estratificados como nível médio (20,9 ± 3; 29,9 ± 10,7; 29,3 ± 8,9 cm respectivamente). Conclusão. Os servidores do Tribunal Superior Eleitoral analisados tiveram valores do índice de massa corpórea e percentual de gordura acima da média, além de baixa força de preensão manual. Registraram-se, porém, flexibilidade e pressão arterial sistólica, diastólica e média classificadas como normal, apesar de alguns homens terem sido estratificados como hipertensos.


Objective. To verify and compare with normative values, the anthropometric, hemodynamic and neuromuscular measurementsof the public servants of the Tribunal Superior Eleitoral of the Distrito Federal. Method. Thirty one subjects (11 men and 20 women) with 32.9 ± 11.8 years underwent measurements of body mass (kg)and height (cm), for subsequent calculation of the body mass index (kg/m2), blood pressure, handgrip strength and flexibility.Results. Servers of the Tribunal Superior Eleitoral (n = 31) were stratified as normal BMI (24.1 ± 4.4 kg/m2), but when the male and female groups were separately analyzed, men were classified as overweight (25, 9 ± 3.5 kg/m2). Regarding the body fat, both groups had elevated average scores (19.3 ± 7.2 and 27.3 ± 4.9% for men and women respectively). The values of systolic (112.9 ± 13 mmHg), diastolic (72.7 ± 10.2 mmHg) and average blood pressure (86.1 ± 10.7 mmHg) were normal.However, 36.4% of men had high blood pressure. The analyzed handgrip strength for the entire sample (25 ± 7.7 kgf) as well as for men (31.1 ± 9 kgf) and women (20.9 ± 3 kgf) was stratified as below the average. In the seat and reach flexibility test, the total sample, men and women separately presented average results (20.9 ± 3, 29.9 ± 10.7, 29.3 ± 8.9 cm respectively). Conclusion. Servers of the Tribunal Superior Eleitoral had elevated average body mass index and body fat percentage,and low handgrip strength. On the other hand, flexibility, systolic and diastolic blood pressures were classified as normal, even though some men were classified as hypertensive.

18.
Psicol. teor. prát ; 10(2): 147-161, dez. 2008.
Article in Portuguese | LILACS | ID: lil-519638

ABSTRACT

Este artigo tematiza articulações teórico-metodológicas entre a Psicologia Comunitária e a Educação Libertadora, discutindo também suas propostas socioideológicas e ético-políticas. Consiste em um desdobramento de uma pesquisa realizada pelo Núcleo de Psicologia Comunitária (Nucom) da Universidade Federal do Ceará, cuja finalidade era contribuir com o desenvolvimento epistemológico do marco teórico-metodológico da Psicologia Comunitária. Para tanto, procedemos a uma revisão teórica, explorando, na trajetória de constituição da Educação Libertadora e da Psicologia Comunitária, o encontro entre ambas as teorias, especificamente no Estado do Ceará. Tal revisão se debruçou ainda sobre elementos teórico-metodológicos, identificando pontos de convergência e integração entre ambas as disciplinas, bem como os fundamentos socioideológicos que refletem sua visão de mundo. Assim, apontamos para uma significativa consistência epistemológica relativa à integração da Educação Libertadora no marco teórico da Psicologia Comunitária, conferindo coesão teórico-metodológica e coerência ético-política a essa práxis psicológica libertadora, a partir do eixo teoria-prática-compromisso social.


This paper is about the theorical methodological links between Community Psychology and Liberating Education, discussing their social ideological and ethical political proposals. It concerns an unfolding of a research conducted by the Núcleo de Psicologia Comunitária (Nucom) of the Universidade Federal do Ceará (UFC), with the intention of contributing to the epistemological development of the theorical methodological milestone of the Community Psychology. In order to reach this aim, we made a theorical revision, exploring, in the trajectory of the constitution of Liberating Education and Community Psychology, the meeting of both theories, specifically in the Ceará state. This review is also based on theorical methodological elements that identify points of convergences and integration between both disciplines, as well as the social ideological foundations which reflect their view of the world. So, we point to a relevant epistemological consistency related to the integration of Liberating Education in the theorical milestone of Community Psychology, giving theorical methodological cohesion and ethical political coherence to this liberating psychological praxis, in the axis of theory, praxis and social compromise.


Este artículo tematiza articulaciones teórico-metodológicas entre la Psicología Comunitaria y la Educación Libertadora, discutiendo también sus propuestas socio-ideológicas y ético-políticas. Consiste en un desdobramiento de una investigación realizada por el Núcleo de Psicología Comunitaria (Nucom) de la Universidad Federal de Ceará, cuya finalidad fué contribuir con el desarrollo epistemológico del marco teórico-metodológico de la Psicología Comunitaria. Para tanto, se procedió con una revisión teórica, explorando en la trayectoria de constitución de la Educación Libertadora y de la Psicología Comunitaria el encuentro entre las dos teorías, especificamente en el estado de Ceará. Tal revisión se foco también sobre elementos teórico-metodológicos, identificando puntos de convergencia e integración entre las dos disciplinas, bien como a los fundamentos sócio- ideológicos que reflejan su visión de mundo. Así, apuntamos para una significativa consistencia epistemológica relativa a la integración de la Educación Libertadora en el marco teórico de la Psicología Comunitaria, confiriéndole coesión teórico-metodológica y coherencia ético-política a esa praxis psicológica libertadora, a partir del eje teoría-práctica-compromiso social.

19.
Indian J Dermatol Venereol Leprol ; 2008 Sep-Oct; 74(5): 478-80
Article in English | IMSEAR | ID: sea-51930

ABSTRACT

Neutrophilic dermatosis of the dorsal hands, a localized form of Sweet's syndrome, was recently described, and can be associated with several diseases including infections. Chronic hepatitis C virus infection has been proposed as a possible triggering factor. The authors present a case in which the clinical and laboratory workup diagnosis only revealed positive serology for hepatitis C virus. Although a cause-effect relation could not be proved, it might be advisable to include serology for this virus in the initial evaluation of patients with neutrophilic dermatosis.

20.
Braz. j. infect. dis ; 11(1): 153-156, Feb. 2007. ilus
Article in English | LILACS | ID: lil-454695

ABSTRACT

The authors present a case from a 59 years old white female Brazilian patient, based in Salvador-Bahia, Brazil's northeastern side area, who experienced irritative cough and progressive dyspnea, and, after 18 months, was admitted to a hospital with respiratory insufficiency. The physical exam showed diffuse rales in both hemithoraces. Initial leukogram showed 14,400 cells/mL with 14 percent of eosinophils and chest X-ray showed peribronchovascular infiltrate, predominating in the lower half of the lung fields, and small opaque nodules. The high-resolution computed tomography scan of the chest (HRCT) presented compatible pattern with airways disease, especially from the small airways, with air trapping, tree sprouting images, central lobular nodules and bronchiectasis, making the results compatible with bronchiolitis and bronchiectasis. The transbroncho biopsy unveiled granulomatous lesion with necrosis, where was noticed a structure compatible to a parasitic case, and the research of the parasite eggs in the sputum was positive to paragonimus. After the praziquantel use, the patient presented a thick ferruginous expectoration and the result for BAAR examination was positive. The PCR exam and the sputum culture confirmed M. tuberculosis, and then the treatment for M. tuberculosis was initiated. The authors warn that this infection may have been a consequence of economics globalization process, where the importation of parasitized crustaceans might be the cause. However, there is the need of an accurate examination for the possibility of paragonimus specimens in this area of Brazil.


Subject(s)
Animals , Female , Humans , Middle Aged , Lung Diseases, Parasitic/epidemiology , Paragonimiasis/epidemiology , Anthelmintics/therapeutic use , Brazil/epidemiology , Lung Diseases, Parasitic/diagnosis , Lung Diseases, Parasitic/drug therapy , Paragonimiasis/diagnosis , Paragonimiasis/drug therapy , Paragonimus/isolation & purification , Praziquantel/therapeutic use
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